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☠️ Common Poisoning Antidotes Quick Reference

UseRapid bedside reference for the targeted antidote. For life-threatening cases, prioritise airway/breathing/ci…

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SourceGoldfrank's Toxicologic Emergencies; poison-control guidance

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋toxOpen scene pack →
Related scores
Matching pathway
🧭dkaOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

Supportive care and decontamination come before the antidote.

When to use

Rapid bedside reference for the targeted antidote. For life-threatening cases, prioritise airway/breathing/circulation, decontamination and a poison-control consult.

How it works

Examples: NAC for acetaminophen; naloxone for opioids; atropine + pralidoxime for organophosphates; fomepizole for toxic alcohols; hydroxocobalamin for cyanide.

Key points

  • Supportive care and decontamination come before the antidote.
  • Methylene blue and rasburicase are cautioned/contraindicated in G6PD deficiency.
  • Long-acting toxins often outlast the antidote — repeat or infuse.
  • Doses must be individualised to the toxin, amount and levels.

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

ToxinMethanol/ethylene glycol

→AntidoteFomepizole (or ethanol) + dialysis

  • Fomepizole：15 mg/kg load → 10 mg/kg q12h
  • Adjuncts：Haemodialysis; folate for methanol, thiamine/pyridoxine for ethylene glycol
ToxinAcetaminophen

→AntidoteNAC (N-acetylcysteine)

  • Dose：IV 150 mg/kg (1 h) → 50 mg/kg (4 h) → 100 mg/kg (16 h), total 300 mg/kg; or oral 140 + 70 ×17
  • Key：Decide by the Rumack-Matthew line; see the 'Acetaminophen' tool
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using Common Poisoning Antidotes Quick Reference?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Common Poisoning Antidotes Quick Reference upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Common Poisoning Antidotes Quick Reference calculated in practice? Can you show a worked example?
Inputs: Toxin Methanol/ethylene glycol → Result: Antidote Fomepizole (or ethanol) + dialysis（Fomepizole: 15 mg/kg load → 10 mg/kg q12h, Adjuncts: Haemodialysis; folate for methanol, thiamine/pyridoxine for ethylene glycol） Inputs: Toxin Acetaminophen → Result: Antidote NAC (N-acetylcysteine)（Dose: IV 150 mg/kg (1 h) → 50 mg/kg (4 h) → 100 mg/kg (16 h), total 300 mg/kg; or oral 140 + 70 ×17, Key: Decide by the Rumack-Matthew line; see the 'Acetaminophen' tool）
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