Lesion Follow-up Comparison (change, doubling time, RECIST target response) — free guideline decision tool
Compare the same lesions across exams: per-lesion change, estimated doubling time and the RECIST 1.1 target response of the sum. Instant, browser-side.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Lesion 1 baseline | 32 mm |
|---|---|
| Lesion 1 current | 24 mm |
| Baseline-to-current interval (for doubling time; optional) | 84 days |
→Target response (RECIST 1.1)SD
- Lesion 1:32 → 24 mm (-8.0 mm, -25.0%)
- Sum of diameters:baseline 32.0 / nadir 32.0 / current 24.0 mm
- vs baseline / vs nadir:-25.0% / -25.0%
Common questions
What is Lesion Follow-up Comparison (change, doubling time, RECIST target response)?
Compare the same lesions across exams: per-lesion change, estimated doubling time and the RECIST 1.1 target response of the sum. Instant, browser-side.
How is Lesion Follow-up Comparison (change, doubling time, RECIST target response) calculated? What is the core formula?
Change = (current − baseline)/baseline; PR ≤ −30% vs baseline; PD ≥ +20% vs nadir and ≥5 mm; doubling time ≈ Δt·ln2 / [3·ln(D2/D1)].
When is Lesion Follow-up Comparison (change, doubling time, RECIST target response) used?
Oncology follow-up, response assessment and re-checks of incidental lesions.
What are the key clinical points for Lesion Follow-up Comparison (change, doubling time, RECIST target response)?
PR: ≥30% decrease from baseline. PD: ≥20% and ≥5 mm increase from nadir. Nodes measured in short axis. Assess non-target and new lesions separately.
What are the limits and cautions when using Lesion Follow-up Comparison (change, doubling time, RECIST target response)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Lesion Follow-up Comparison (change, doubling time, RECIST target response) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Lesion Follow-up Comparison (change, doubling time, RECIST target response) calculated in practice? Can you show a worked example?
Inputs: Lesion 1 baseline 32 mm, Lesion 1 current 24 mm, Baseline-to-current interval (for doubling time; optional) 84 days → Result: Target response (RECIST 1.1) SD(Lesion 1: 32 → 24 mm (-8.0 mm, -25.0%), Sum of diameters: baseline 32.0 / nadir 32.0 / current 24.0 mm, vs baseline / vs nadir: -25.0% / -25.0%)
Run Lesion Follow-up Comparison (change, doubling time, RECIST target response) now
Compare the same lesions across exams: per-lesion change, estimated doubling time and the RECIST 1.1 target response of the sum. Instant, browser-side.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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