🩸 WPSS (MDS WHO Classification-Based)
UseWhen to use: MDS counseling when WHO morphology, cytogenetics, and transfusion dependence are known.
Strata0 very low → 5–6 very high; higher scores associate with poorer survival / AML evolution risk.
LimitsWhen not to use: after AML transformation pathways. · Pitfall: outdated WHO label mapping. · Not a sole transplant order.
SourceWPSS (Malcovati) WHO classification-based MDS score
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
WHO + karyotype + transfusion.
When to use
When to use: MDS counseling when WHO morphology, cytogenetics, and transfusion dependence are known.
How it works
WHO 0–3 + karyotype 0–2 + regular transfusion 0–1 (max 6).
Key points
- WHO + karyotype + transfusion.
- Dynamic over time.
- Next: IPSS-R / IPSS-M.
References
- [Guideline / primary source]WPSS (Malcovati) WHO classification-based MDS score
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| WHO category | 1 — RCMD / RCMD-RS |
|---|---|
| Karyotype risk | 1 — intermediate |
| Regular RBC transfusion need | 0 — no |
→WPSS2/6
- Risk band：2 — intermediate
| WHO category | 0 — RA / RARS / 5q− |
|---|---|
| Karyotype risk | 0 — good |
| Regular RBC transfusion need | 0 — no |
→WPSS0/6
- Risk band：0 — very low
Verification & sources · governance
FAQ
Frequently asked questions
- Does WPSS (MDS WHO Classification-Based) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is WPSS (MDS WHO Classification-Based) calculated in practice? Can you show a worked example?
- Inputs: WHO category 1 — RCMD / RCMD-RS, Karyotype risk 1 — intermediate, Regular RBC transfusion need 0 — no → Result: WPSS 2 /6（Risk band: 2 — intermediate） Inputs: WHO category 0 — RA / RARS / 5q−, Karyotype risk 0 — good, Regular RBC transfusion need 0 — no → Result: WPSS 0 /6（Risk band: 0 — very low）