🩸 Sokal Index (Chronic Myeloid Leukemia)
UseEnter age, spleen size below the costal margin (cm), platelet count, and peripheral blood blast percentage; t…
SourceSokal JE, et al. Prognostic discrimination in 'good-risk' chronic granulocytic leukemia. Blood. 198…
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
The index predates tyrosine kinase inhibitors, so it is now interpreted alongside the Hasford/Euro, EUTOS, and ELTS scores rather than used in isolation (original synthesis · not guideline verbatim).
When to use
Enter age, spleen size below the costal margin (cm), platelet count, and peripheral blood blast percentage; the tool returns the relative-risk value and risk group.
How it works
Exp[0.0116 × (age − 43.4) + 0.0345 × (spleen − 7.51) + 0.188 × ((platelets/700)² − 0.563) + 0.0887 × (blasts − 2.10)]. <0.8 low, 0.8–1.2 intermediate, >1.2 high risk.
Key points
- The index predates tyrosine kinase inhibitors, so it is now interpreted alongside the Hasford/Euro, EUTOS, and ELTS scores rather than used in isolation (original synthesis · not guideline verbatim).
- Spleen size is the maximum distance palpable below the costal margin in centimetres, measured before any treatment.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | 50 years |
|---|---|
| Spleen size (below costal margin) | 5 cm |
| Platelets | 400 ×10⁹/L |
| Peripheral blood blasts | 2 % |
→Sokal relative risk0.94
- Risk group：Intermediate risk
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Sokal Index (Chronic Myeloid Leukemia)?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Sokal Index (Chronic Myeloid Leukemia) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Sokal Index (Chronic Myeloid Leukemia) calculated in practice? Can you show a worked example?
- Inputs: Age 50 years, Spleen size (below costal margin) 5 cm, Platelets 400 ×10⁹/L, Peripheral blood blasts 2 % → Result: Sokal relative risk 0.94（Risk group: Intermediate risk）