🦋 SLICC 2012 SLE Classification Criteria
UseWhen to use: structured classification in suspected SLE for research/epidemiology-aligned documentation.
StrataClassifies vs does not classify — still not a standalone clinical diagnosis.
LimitsWhen not to use: as the only basis to start or stop immunosuppression. · Pitfall: counting the same manifestation twice across overlapping ite… · Mimics (infection, drug-induced, other CTD) must be excluded clinical…
Source中华医学会风湿病学分会 SLE 诊疗相关规范 on zh pages
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Classification ≠ diagnosis.
When to use
When to use: structured classification in suspected SLE for research/epidemiology-aligned documentation.
How it works
≥ 4 criteria with ≥ 1 clinical and ≥ 1 immunologic, OR biopsy-proven LN with ANA or anti-dsDNA.
Key points
- Classification ≠ diagnosis.
- Biopsy rule needs ANA or anti-dsDNA.
- Next: organ-threat work-up; ACR/EULAR 2019 criteria may be used locally as alternative.
References
- [Guideline / primary source]中华医学会风湿病学分会 SLE 诊疗相关规范 on zh pages
- Petri M, et al. Arthritis Rheum 2012 (SLICC)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Acute cutaneous lupus | No |
|---|---|
| Chronic cutaneous lupus | No |
| Oral or nasal ulcers | No |
| Nonscarring alopecia | No |
| Synovitis (≥ 2 joints) or tenderness + morning stiffness | No |
| Serositis | No |
| Renal (proteinuria or red-cell casts) | No |
| Neurologic (seizures, psychosis, mononeuritis…) | No |
| Hemolytic anemia | No |
| Leukopenia or lymphopenia | No |
| Thrombocytopenia | No |
| ANA above lab reference | No |
| Anti-dsDNA above lab reference | No |
| Anti-Sm | No |
| Antiphospholipid antibody (any) | No |
| Low complement (C3, C4 or CH50) | No |
| Direct Coombs positive (without hemolytic anemia) | No |
| Biopsy-proven lupus nephritis | No |
→SLICC 2012Does not classify
- Clinical criteria：0
- Immunologic criteria：0
- Biopsy rule：Not met
| Acute cutaneous lupus | Yes |
|---|---|
| Chronic cutaneous lupus | Yes |
| Oral or nasal ulcers | Yes |
| Nonscarring alopecia | Yes |
| Synovitis (≥ 2 joints) or tenderness + morning stiffness | Yes |
| Serositis | Yes |
| Renal (proteinuria or red-cell casts) | Yes |
| Neurologic (seizures, psychosis, mononeuritis…) | Yes |
| Hemolytic anemia | Yes |
| Leukopenia or lymphopenia | Yes |
| Thrombocytopenia | Yes |
| ANA above lab reference | Yes |
| Anti-dsDNA above lab reference | Yes |
| Anti-Sm | Yes |
| Antiphospholipid antibody (any) | Yes |
| Low complement (C3, C4 or CH50) | Yes |
| Direct Coombs positive (without hemolytic anemia) | Yes |
| Biopsy-proven lupus nephritis | Yes |
→SLICC 2012Classifies as SLE
- Clinical criteria：11
- Immunologic criteria：6
- Biopsy rule：Met (LN + ANA/anti-dsDNA)
Verification & sources · governance
FAQ
Frequently asked questions
- Does SLICC 2012 SLE Classification Criteria upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is SLICC 2012 SLE Classification Criteria calculated in practice? Can you show a worked example?
- Inputs: Acute cutaneous lupus No, Chronic cutaneous lupus No, Oral or nasal ulcers No, Nonscarring alopecia No, Synovitis (≥ 2 joints) or tenderness + morning stiffness No, Serositis No, Renal (proteinuria or red-cell casts) No, Neurologic (seizures, psychosis, mononeuritis…) No… → Result: SLICC 2012 Does not classify（Clinical criteria: 0, Immunologic criteria: 0, Biopsy rule: Not met） Inputs: Acute cutaneous lupus Yes, Chronic cutaneous lupus Yes, Oral or nasal ulcers Yes, Nonscarring alopecia Yes, Synovitis (≥ 2 joints) or tenderness + morning stiffness Yes, Serositis Yes, Renal (proteinuria or red-cell casts) Yes, Neurologic (seizures, psychosis, mononeuritis…) Yes… → Result: SLICC 2012 Classifies as SLE（Clinical criteria: 11, Immunologic criteria: 6, Biopsy rule: Met (LN + ANA/anti-dsDNA)）