🦋 SLEDAI-2K (SLE Disease Activity)
UseWhen to use: longitudinal activity monitoring in classified SLE.
StrataHigher totals = more activity; band cut-offs are communicative aids, not treatment mandates.
LimitsWhen not to use: as classification (use SLICC/ACR-EULAR) or to ignore… · Pitfall: scoring infection-related findings as lupus activity. · Clinician global assessment still required.
Source中华医学会风湿病学分会 SLE 诊疗规范 on zh
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Weighted public items.
When to use
When to use: longitudinal activity monitoring in classified SLE.
How it works
Sum published weights (8/4/2/1 items) for descriptors present in the past 10 days per SLEDAI-2K rules.
Key points
- Weighted public items.
- 10-day window / 2K persistence rules.
- Next: SLICC classification; organ-specific pathways.
References
- [Guideline / primary source]中华医学会风湿病学分会 SLE 诊疗规范 on zh
- Gladman DD, et al. J Rheumatol 2002 (SLEDAI-2K)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Seizure (8) | No |
|---|---|
| Psychosis (8) | No |
| Organic brain syndrome (8) | No |
| Visual disturbance (8) | No |
| Cranial nerve disorder (8) | No |
| Lupus headache (8) | No |
| CVA (8) | No |
| Vasculitis (8) | No |
| Arthritis (4) | No |
| Myositis (4) | No |
| Urinary casts (4) | No |
| Hematuria (4) | No |
| Proteinuria (4) | No |
| Pyuria (4) | No |
| Rash (2) | No |
| Alopecia (2) | No |
| Mucosal ulcers (2) | No |
| Pleurisy (2) | No |
| Pericarditis (2) | No |
| Low complement (2) | No |
| Increased DNA binding (2) | No |
| Fever (1) | No |
| Thrombocytopenia (1) | No |
| Leukopenia (1) | No |
→SLEDAI-2K0
- Activity band (commonly used)：No activity (0)
- Window：Descriptors present within the past 10 days (SLEDAI-2K rules)
| Seizure (8) | Yes |
|---|---|
| Psychosis (8) | Yes |
| Organic brain syndrome (8) | Yes |
| Visual disturbance (8) | Yes |
| Cranial nerve disorder (8) | Yes |
| Lupus headache (8) | Yes |
| CVA (8) | Yes |
| Vasculitis (8) | Yes |
| Arthritis (4) | Yes |
| Myositis (4) | Yes |
| Urinary casts (4) | Yes |
| Hematuria (4) | Yes |
| Proteinuria (4) | Yes |
| Pyuria (4) | Yes |
| Rash (2) | Yes |
| Alopecia (2) | Yes |
| Mucosal ulcers (2) | Yes |
| Pleurisy (2) | Yes |
| Pericarditis (2) | Yes |
| Low complement (2) | Yes |
| Increased DNA binding (2) | Yes |
| Fever (1) | Yes |
| Thrombocytopenia (1) | Yes |
| Leukopenia (1) | Yes |
→SLEDAI-2K105
- Activity band (commonly used)：Very high (≥20)
- Window：Descriptors present within the past 10 days (SLEDAI-2K rules)
Verification & sources · governance
FAQ
Frequently asked questions
- Does SLEDAI-2K (SLE Disease Activity) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is SLEDAI-2K (SLE Disease Activity) calculated in practice? Can you show a worked example?
- Inputs: Seizure (8) No, Psychosis (8) No, Organic brain syndrome (8) No, Visual disturbance (8) No, Cranial nerve disorder (8) No, Lupus headache (8) No, CVA (8) No, Vasculitis (8) No… → Result: SLEDAI-2K 0（Activity band (commonly used): No activity (0), Window: Descriptors present within the past 10 days (SLEDAI-2K rules)） Inputs: Seizure (8) Yes, Psychosis (8) Yes, Organic brain syndrome (8) Yes, Visual disturbance (8) Yes, Cranial nerve disorder (8) Yes, Lupus headache (8) Yes, CVA (8) Yes, Vasculitis (8) Yes… → Result: SLEDAI-2K 105（Activity band (commonly used): Very high (≥20), Window: Descriptors present within the past 10 days (SLEDAI-2K rules)）