What is SEDAN Score (Post-tPA Hemorrhage)?

Estimate post-tPA symptomatic ICH risk with SEDAN (glucose, CT signs, age, NIHSS).

How is SEDAN Score (Post-tPA Hemorrhage) calculated? What is the core formula?

Glucose (≤8.0=0, 8.1–12=1, >12 mmol/L=2) + early infarct signs (1) + dense artery (1) + age >75 (1) + NIHSS ≥10 (1). 0–6. Use labs and baseline CT/NIHSS before or at thrombolysis decision.

What are the key clinical points for SEDAN Score (Post-tPA Hemorrhage)?

Mnemonic: Sugar, Early infarct, Dense artery, Age, NIHSS. 0–6. Next: HAT / ASPECTS.

What are the limits and cautions when using SEDAN Score (Post-tPA Hemorrhage)?

When not to use: as sole exclusion from guideline-eligible lytics. Pitfall: mmol vs mg/dL glucose mix-ups. Does not replace door-to-needle process discipline. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

Does SEDAN Score (Post-tPA Hemorrhage) upload patient data? Where is it calculated?

Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.

How is SEDAN Score (Post-tPA Hemorrhage) calculated in practice? Can you show a worked example?

Inputs: Blood glucose 8.1–12.0 mmol/L (1), Early infarct signs on admission CT No (0), Hyperdense artery sign No (0), Age > 75 y No (0), NIHSS ≥ 10 No (0) → Result: SEDAN 1 /6（Band: Lower sICH risk band, Components: Sugar, Early infarct, Dense artery, Age, NIHSS） Inputs: Blood glucose ≤ 8.0 mmol/L (≤144 mg/dL) (0), Early infarct signs on admission CT No (0), Hyperdense artery sign No (0), Age > 75 y No (0), NIHSS ≥ 10 No (0) → Result: SEDAN 0 /6（Band: Lower sICH risk band, Components: Sugar, Early infarct, Dense artery, Age, NIHSS）

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🧠 SEDAN Score (Post-tPA Hemorrhage)

UseWhen to use: IV thrombolysis risk discussion in acute ischemic stroke.

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StrataHigher SEDAN associated with higher sICH. Use with HAT and local protocols.

LimitsWhen not to use: as sole exclusion from guideline-eligible lytics. · Pitfall: mmol vs mg/dL glucose mix-ups. · Does not replace door-to-needle process discipline.

SourceStrbian D, et al. Neurology 2012 (SEDAN)

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.

Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step

📋Stroke codeOpen scene pack →

Related scores

Matching pathway

🧭strokeOpen pathway →

Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes

Clinical takeaway

Mnemonic: Sugar, Early infarct, Dense artery, Age, NIHSS.

When to use

When to use: IV thrombolysis risk discussion in acute ischemic stroke.

How it works

Glucose (≤8.0=0, 8.1–12=1, >12 mmol/L=2) + early infarct signs (1) + dense artery (1) + age >75 (1) + NIHSS ≥10 (1). 0–6.

Key points

Mnemonic: Sugar, Early infarct, Dense artery, Age, NIHSS.
0–6.
Next: HAT / ASPECTS.

References

Strbian D, et al. Neurology 2012 (SEDAN)

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Blood glucose	8.1–12.0 mmol/L (1)
Early infarct signs on admission CT	No (0)
Hyperdense artery sign	No (0)
Age > 75 y	No (0)
NIHSS ≥ 10	No (0)

→SEDAN1/6

Band：Lower sICH risk band
Components：Sugar, Early infarct, Dense artery, Age, NIHSS

Blood glucose	≤ 8.0 mmol/L (≤144 mg/dL) (0)
Early infarct signs on admission CT	No (0)
Hyperdense artery sign	No (0)
Age > 75 y	No (0)
NIHSS ≥ 10	No (0)

→SEDAN0/6

Band：Lower sICH risk band
Components：Sugar, Early infarct, Dense artery, Age, NIHSS

Verification & sources · governance

FAQ

Frequently asked questions

Does SEDAN Score (Post-tPA Hemorrhage) upload patient data? Where is it calculated?: Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is SEDAN Score (Post-tPA Hemorrhage) calculated in practice? Can you show a worked example?: Inputs: Blood glucose 8.1–12.0 mmol/L (1), Early infarct signs on admission CT No (0), Hyperdense artery sign No (0), Age > 75 y No (0), NIHSS ≥ 10 No (0) → Result: SEDAN 1 /6（Band: Lower sICH risk band, Components: Sugar, Early infarct, Dense artery, Age, NIHSS） Inputs: Blood glucose ≤ 8.0 mmol/L (≤144 mg/dL) (0), Early infarct signs on admission CT No (0), Hyperdense artery sign No (0), Age > 75 y No (0), NIHSS ≥ 10 No (0) → Result: SEDAN 0 /6（Band: Lower sICH risk band, Components: Sugar, Early infarct, Dense artery, Age, NIHSS）

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