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🩸 Reticulocyte Production Index (RPI)

UseDistinguish hypoproliferative from hyperproliferative anaemia.

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SourceStandard haematology references (RPI)

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Scene next step
📋hematologyOpen scene pack →
Related scores
Matching pathway
🧭febrile_neutropeniaOpen pathway →
Score + version; reference only — not a substitute for care · no HIS write

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Methodology · worked example, guidelines & full notes
Clinical takeaway

RPI ≥ 2–3 indicates an adequate marrow response.

When to use

Distinguish hypoproliferative from hyperproliferative anaemia.

How it works

RPI = (reticulocyte% × Hct/45) / maturation factor (1–2.5 by Hct).

Key points

  • RPI ≥ 2–3 indicates an adequate marrow response.
  • RPI < 2 suggests hypoproliferative anaemia.
  • Corrects for anaemia severity and maturation.

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Reticulocyte3 %
Haematocrit30 %

→RPI1.3

  • Corrected reticulocyte：2.0%
  • Maturation factor：1.5
  • Interpretation：< 2 — inadequate response (hypoproliferative anaemia).
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using Reticulocyte Production Index (RPI)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Reticulocyte Production Index (RPI) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Reticulocyte Production Index (RPI) calculated in practice? Can you show a worked example?
Inputs: Reticulocyte 3 %, Haematocrit 30 % → Result: RPI 1.3（Corrected reticulocyte: 2.0%, Maturation factor: 1.5, Interpretation: < 2 — inadequate response (hypoproliferative anaemia).）
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