🩸 Rai Staging (CLL)
UseWhen to use: CLL baseline or restaging alongside Binet.
Strata0 low; I–II intermediate; III–IV high in classic risk grouping.
LimitsWhen not to use: anemia from other causes unlabeled. · Pitfall: skipping CLL confirmation. · Not a sole therapy order.
SourceRai CLL clinical staging system
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Stages 0–IV.
When to use
When to use: CLL baseline or restaging alongside Binet.
How it works
0 lymphocytosis; I nodes; II hepato/splenomegaly; III anemia; IV thrombocytopenia.
Key points
- Stages 0–IV.
- III/IV high-risk classic.
- Next: Binet / IWCLL / TP53.
References
- Rai CLL clinical staging system
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Lymphadenopathy | No |
|---|---|
| Spleen and/or liver enlargement | No |
| Anemia (Hb <11 g/dL) | No |
| Thrombocytopenia (Plt <100 ×10⁹/L) | No |
→Rai0
- Cue：Lymphocytosis only — Rai 0 (low-risk classic grouping)
| Lymphadenopathy | Yes |
|---|---|
| Spleen and/or liver enlargement | Yes |
| Anemia (Hb <11 g/dL) | Yes |
| Thrombocytopenia (Plt <100 ×10⁹/L) | Yes |
→RaiIV
- Cue：Thrombocytopenia — Rai IV (high-risk classic grouping)
Verification & sources · governance
FAQ
Frequently asked questions
- Does Rai Staging (CLL) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Rai Staging (CLL) calculated in practice? Can you show a worked example?
- Inputs: Lymphadenopathy No, Spleen and/or liver enlargement No, Anemia (Hb <11 g/dL) No, Thrombocytopenia (Plt <100 ×10⁹/L) No → Result: Rai 0（Cue: Lymphocytosis only — Rai 0 (low-risk classic grouping)） Inputs: Lymphadenopathy Yes, Spleen and/or liver enlargement Yes, Anemia (Hb <11 g/dL) Yes, Thrombocytopenia (Plt <100 ×10⁹/L) Yes → Result: Rai IV（Cue: Thrombocytopenia — Rai IV (high-risk classic grouping)）