🩸 IPSS-R (Revised MDS)
UseWhen to use: baseline MDS risk before disease-modifying therapy.
StrataHigher IPSS-R predicts shorter survival and higher AML progression risk.
LimitsWhen not to use: treated / secondary AML contexts without caveat. · Pitfall: wrong cytogenetic family. · Not a sole transplant order.
SourceIPSS-R (Greenberg) revised MDS prognostic scoring system
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Five components.
When to use
When to use: baseline MDS risk before disease-modifying therapy.
How it works
Cytogenetics + blasts + Hb + platelets + ANC points → very low to very high bands.
Key points
- Five components.
- ≤1.5 to >6 bands.
- Next: molecular IPSS-M.
References
- IPSS-R (Greenberg) revised MDS prognostic scoring system
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Cytogenetic risk | Intermediate (2) |
|---|---|
| Bone-marrow blasts % | >2–<5% (1) |
| Hemoglobin (g/dL) | 8–<10 (1) |
| Platelets (×10⁹/L) | 50–<100 (0.5) |
| ANC (×10⁹/L) | ≥0.8 (0) |
→IPSS-R4.5
- Risk band：>3–4.5 — intermediate
| Cytogenetic risk | Very good (0) |
|---|---|
| Bone-marrow blasts % | ≤2% (0) |
| Hemoglobin (g/dL) | ≥10 (0) |
| Platelets (×10⁹/L) | ≥100 (0) |
| ANC (×10⁹/L) | ≥0.8 (0) |
→IPSS-R0.0
- Risk band：≤1.5 — very low
Verification & sources · governance
FAQ
Frequently asked questions
- Does IPSS-R (Revised MDS) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is IPSS-R (Revised MDS) calculated in practice? Can you show a worked example?
- Inputs: Cytogenetic risk Intermediate (2), Bone-marrow blasts % >2–<5% (1), Hemoglobin (g/dL) 8–<10 (1), Platelets (×10⁹/L) 50–<100 (0.5), ANC (×10⁹/L) ≥0.8 (0) → Result: IPSS-R 4.5（Risk band: >3–4.5 — intermediate） Inputs: Cytogenetic risk Very good (0), Bone-marrow blasts % ≤2% (0), Hemoglobin (g/dL) ≥10 (0), Platelets (×10⁹/L) ≥100 (0), ANC (×10⁹/L) ≥0.8 (0) → Result: IPSS-R 0.0（Risk band: ≤1.5 — very low）