🩸 Glucose Control in Critically Ill Patients
UseUse in the ICU to select a blood-glucose target band and decide when to start IV insulin infusion, with atten…
SourceNICE-SUGAR Investigators. Intensive vs conventional glucose control. N Engl J Med 2009.
This-shift next steps
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Methodology · worked example, guidelines & full notes
A moderate target (140–180 mg/dL [unverified]) balances the harms of hyperglycemia against the hypoglycemia risk of tight control (original synthesis · not guideline verbatim).
When to use
Use in the ICU to select a blood-glucose target band and decide when to start IV insulin infusion, with attention to avoiding hypoglycemia.
How it works
Target generally 140–180 mg/dL (7.8–10.0 mmol/L) [unverified] for most critically ill; start or intensify IV insulin at ≥ 180 mg/dL (10 mmol/L) (SSC 2026 Rec. 92); avoid tight control (80–110) due to hypoglycemia harm; monitor frequently.
Key points
- A moderate target (140–180 mg/dL [unverified]) balances the harms of hyperglycemia against the hypoglycemia risk of tight control (original synthesis · not guideline verbatim).
- Tight glucose control (NICE-SUGAR) increased severe hypoglycemia and mortality, so it is no longer recommended.
- Frequent point-of-care monitoring and a validated infusion protocol reduce both hyper- and hypoglycemic excursions.
References
- [Guideline / primary source]NICE-SUGAR Investigators. Intensive vs conventional glucose control. N Engl J Med 2009.
- [Guideline / primary source]Surviving Sepsis Campaign 2021 — glycemic control.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Current glucose | 200 |
|---|---|
| Unit | mg/dL |
| Population | Most critically ill patients (target 140–180 [unverified]) |
→Glucose200 mg/dL
- Glucose:200 mg/dL (11.1 mmol/L)
- Target range:Standard 140–180 mg/dL (7.8–10.0 mmol/L) [unverified]
- Status / management:Above target — ≥ 180 mg/dL (10 mmol/L): start or intensify IV insulin (SSC 2026 Rec. 92); investigate DKA/HHS, infection, steroids/parenteral nutrition and other triggers
| Current glucose | 200 |
|---|---|
| Unit | mmol/L |
| Population | Selected populations — postop/cardiac/neuro |
→Glucose3600 mg/dL
- Glucose:3600 mg/dL (200 mmol/L)
- Target range:pending update
- Status / management:Above target — ≥ 180 mg/dL (10 mmol/L): start or intensify IV insulin (SSC 2026 Rec. 92); investigate DKA/HHS, infection, steroids/parenteral nutrition and other triggers
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Glucose Control in Critically Ill Patients?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Glucose Control in Critically Ill Patients upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Glucose Control in Critically Ill Patients calculated in practice? Can you show a worked example?
- Inputs: Current glucose 200, Unit mg/dL, Population Most critically ill patients (target 140–180 [unverified]) → Result: Glucose 200 mg/dL(Glucose: 200 mg/dL (11.1 mmol/L), Target range: Standard 140–180 mg/dL (7.8–10.0 mmol/L) [unverified], Status / management: Above target — ≥ 180 mg/dL (10 mmol/L): start or intensify IV insulin (SSC 2026 Rec. 92); investigate DKA/HHS, infection, steroids/parenteral nutrition and other triggers) Inputs: Current glucose 200, Unit mmol/L, Population Selected populations — postop/cardiac/neuro → Result: Glucose 3600 mg/dL(Glucose: 3600 mg/dL (200 mmol/L), Target range: pending update, Status / management: Above target — ≥ 180 mg/dL (10 mmol/L): start or intensify IV insulin (SSC 2026 Rec. 92); investigate DKA/HHS, infection, steroids/parenteral nutrition and other triggers)