🩸 HERDOO2 Rule (Women, Unprovoked VTE)
UseWhen to use: women completing 5–12 months AC for unprovoked VTE, VIDAS D-dimer available on therapy.
Strata≤1 low-risk discontinue discussion; ≥2 usually continue unless bleed risk dominates.
LimitsWhen not to use: men, provoked VTE, cancer, APS. · Pitfall: wrong D-dimer assay/cutoff. · Shared decision still required.
SourceRodger MA et al. HERDOO2 rule
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Women only.
When to use
When to use: women completing 5–12 months AC for unprovoked VTE, VIDAS D-dimer available on therapy.
How it works
HER (hyperpigmentation/edema/redness) + D-dimer ≥250 + BMI≥30 + age≥65 (0–4).
Key points
- Women only.
- ≤1 low-risk band.
- Next: VTE-BLEED / preference talk.
References
- Rodger MA et al. HERDOO2 rule
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Patient is female (HERDOO2 derives in women only) | Yes — female |
|---|---|
| Hyperpigmentation, edema, OR redness of either leg | Yes (+1) |
| VIDAS D-dimer ≥250 μg/L while on anticoagulation | Yes (+1) |
| Obesity (BMI ≥30 kg/m²) | Yes (+1) |
| Older age (≥65 years) | Yes (+1) |
→HERDOO24/4
- Cue：≥2 — not low-risk by HERDOO2; usually continue anticoagulation unless bleed risk dominates
Verification & sources · governance
FAQ
Frequently asked questions
- Does HERDOO2 Rule (Women, Unprovoked VTE) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is HERDOO2 Rule (Women, Unprovoked VTE) calculated in practice? Can you show a worked example?
- Inputs: Patient is female (HERDOO2 derives in women only) Yes — female, Hyperpigmentation, edema, OR redness of either leg Yes (+1), VIDAS D-dimer ≥250 μg/L while on anticoagulation Yes (+1), Obesity (BMI ≥30 kg/m²) Yes (+1), Older age (≥65 years) Yes (+1) → Result: HERDOO2 4 /4（Cue: ≥2 — not low-risk by HERDOO2; usually continue anticoagulation unless bleed risk dominates）