🩸 HCT-CI (Hematopoietic Cell Transplant Comorbidity Index)
UseWhen to use: allo-HCT counseling and NRM risk banding.
StrataHigher HCT-CI associates with higher non-relapse mortality; center outcomes vary.
LimitsWhen not to use: replacing full transplant committee judgment. · Pitfall: double-counting hepatic/pulmonary tiers. · Not a sole ineligibility decree.
SourceHCT-CI (Sorror) hematopoietic cell transplantation comorbidity index
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Weighted comorbidities.
When to use
When to use: allo-HCT counseling and NRM risk banding.
How it works
Weighted sum of 17 comorbidity categories (1/2/3 points); bands 0 / 1–2 / ≥3.
Key points
- Weighted comorbidities.
- 0 / 1–2 / ≥3 bands.
- Next: DRI / center outcomes.
References
- HCT-CI (Sorror) hematopoietic cell transplantation comorbidity index
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Arrhythmia (1) | No |
|---|---|
| Cardiac (CAD/CHF/MI/EF ≤50%) (1) | No |
| Inflammatory bowel disease (1) | No |
| Diabetes on meds (1) | No |
| Cerebrovascular disease (1) | No |
| Psychiatric disturbance (1) | No |
| Hepatic | Mild (+1) |
| Obesity BMI >35 (1) | No |
| Infection requiring ongoing antimicrobials (1) | No |
| Rheumatologic (2) | No |
| Peptic ulcer requiring treatment (2) | No |
| Moderate/severe renal (2) | No |
| Pulmonary | Moderate DLCO/FEV1 66–80% or DOE slight (+2) |
| Prior solid tumor (3) | No |
| Heart valve disease (3) | No |
→HCT-CI3
- Cue：>2 — high risk band
| Arrhythmia (1) | No |
|---|---|
| Cardiac (CAD/CHF/MI/EF ≤50%) (1) | No |
| Inflammatory bowel disease (1) | No |
| Diabetes on meds (1) | No |
| Cerebrovascular disease (1) | No |
| Psychiatric disturbance (1) | No |
| Hepatic | None (0) |
| Obesity BMI >35 (1) | No |
| Infection requiring ongoing antimicrobials (1) | No |
| Rheumatologic (2) | No |
| Peptic ulcer requiring treatment (2) | No |
| Moderate/severe renal (2) | No |
| Pulmonary | None (0) |
| Prior solid tumor (3) | No |
| Heart valve disease (3) | No |
→HCT-CI0
- Cue：0 — low risk band (teaching)
Verification & sources · governance
FAQ
Frequently asked questions
- Does HCT-CI (Hematopoietic Cell Transplant Comorbidity Index) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is HCT-CI (Hematopoietic Cell Transplant Comorbidity Index) calculated in practice? Can you show a worked example?
- Inputs: Arrhythmia (1) No, Cardiac (CAD/CHF/MI/EF ≤50%) (1) No, Inflammatory bowel disease (1) No, Diabetes on meds (1) No, Cerebrovascular disease (1) No, Psychiatric disturbance (1) No, Hepatic Mild (+1), Obesity BMI >35 (1) No… → Result: HCT-CI 3（Cue: >2 — high risk band） Inputs: Arrhythmia (1) No, Cardiac (CAD/CHF/MI/EF ≤50%) (1) No, Inflammatory bowel disease (1) No, Diabetes on meds (1) No, Cerebrovascular disease (1) No, Psychiatric disturbance (1) No, Hepatic None (0), Obesity BMI >35 (1) No… → Result: HCT-CI 0（Cue: 0 — low risk band (teaching)）