🩸 Hasford (Euro) Score — CML
UseWhen to use: pre-treatment CML-CP baseline risk alongside Sokal/EUTOS/ELTS.
Strata≤780 low; 781–1480 intermediate; >1480 high.
LimitsWhen not to use: after therapy start / late CP. · Pitfall: spleen measured after cytoreduction. · Not a sole TKI choice.
SourceHasford Euro CML relative-risk score (J Natl Cancer Inst 1998)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Euro/Hasford.
When to use
When to use: pre-treatment CML-CP baseline risk alongside Sokal/EUTOS/ELTS.
How it works
1000×[0.6666·(age≥50)+0.042·spleen+0.0584·blasts+0.0413·eos+0.2039·(baso≥3%)+1.0956·(plt≥1500)].
Key points
- Euro/Hasford.
- Pre-treatment only.
- Next: ELTS / molecular response.
References
- Hasford Euro CML relative-risk score (J Natl Cancer Inst 1998)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | 52 years |
|---|---|
| Spleen below costal margin | 5 cm |
| Peripheral blasts | 2 % |
| Eosinophils | 3 % |
| Basophils | 2 % |
| Platelets | 400 ×10⁹/L |
→Hasford score1117
- Linear predictor:1.1173
- Cue:781–1480 — intermediate risk
Verification & sources · governance
FAQ
Frequently asked questions
- Does Hasford (Euro) Score — CML upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Hasford (Euro) Score — CML calculated in practice? Can you show a worked example?
- Inputs: Age 52 years, Spleen below costal margin 5 cm, Peripheral blasts 2 %, Eosinophils 3 %, Basophils 2 %, Platelets 400 ×10⁹/L → Result: Hasford score 1117(Linear predictor: 1.1173, Cue: 781–1480 — intermediate risk)