Home › Clinical Tools › Fluid Responsiveness

💧 Fluid Responsiveness Assessment

UseUse during resuscitation to test responsiveness via passive leg raise, fluid challenge, or PPV/SVV before giv…

Loading calculator…

SourceSurviving Sepsis Campaign 2021 — dynamic measures.

Runs locally in your browser (no PHI uploaded). For licensed clinicians — not a substitute for clinical judgement.
Stored on this device for revisit reminders

This-shift next steps

After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.

Score + version; reference only — not a substitute for care · no HIS write

Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.

Methodology · worked example, guidelines & full notes
Clinical takeaway

PPV/SVV is only valid with controlled mechanical ventilation, sinus rhythm, and no spontaneous breathing — otherwise use PLR or a fluid challenge (original synthesis · not guideline verbatim).

When to use

Use during resuscitation to test responsiveness via passive leg raise, fluid challenge, or PPV/SVV before giving more fluid.

How it works

Passive leg raise or 250–500 mL fluid challenge increasing stroke volume/cardiac output ≥ 10%, or PPV/SVV (with applicability conditions), indicates fluid responsiveness; dynamic indices outperform static CVP.

Key points

  • PPV/SVV is only valid with controlled mechanical ventilation, sinus rhythm, and no spontaneous breathing — otherwise use PLR or a fluid challenge (original synthesis · not guideline verbatim).
  • Responsiveness alone does not mandate fluids; give them only with concurrent signs of hypoperfusion.
  • Static CVP predicts fluid responsiveness poorly and should not drive fluid decisions.

References

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Assessment methodFluid challenge (250–500 mL, measure SV change)
Value (PLR/challenge = SV or CO increase %; PPV/SVV = variation %)12 %
PPV/SVV applicability (mechanical ventilation Vt, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension)Met (or not a PPV/SVV method)

→Fluid responsivenessResponsive

  • Determination:Fluid challenge (250–500 mL) produced a stroke-volume increase of 12% (threshold ≥ 10%) → fluid-responsive (a fluid bolus may increase cardiac output)
  • Management direction:With evidence of hypoperfusion (high lactate/oliguria/prolonged CRT), give fluids cautiously and reassess; stop volume expansion once non-responsive or perfusion improves
  • Note:Dynamic indices outperform static (CVP/single pressure predicts poorly). PLR and fluid challenge directly measure SV/CO change and remain applicable with spontaneous breathing and arrhythmia; PPV/SVV requires mechanical ventilation, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension. Give fluids on this basis only with signs of hypoperfusion
Assessment methodPPV / SVV (pulse-pressure / stroke-volume variation)
Value (PLR/challenge = SV or CO increase %; PPV/SVV = variation %)12 %
PPV/SVV applicability (mechanical ventilation Vt, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension)Not met

→PPV/SVVUnreliable

  • Determination:PPV/SVV is reliable only with mechanical ventilation, sinus rhythm, no spontaneous breathing trigger, and no severe right-heart failure/intra-abdominal hypertension; the current conditions are not met
  • Recommendation:Switch to passive leg raise (PLR) or fluid challenge (directly measuring stroke-volume/cardiac-output change), which remain applicable with spontaneous breathing/arrhythmia
  • Basis:Dynamic indices outperform static (CVP predicts poorly); PPV/SVV applicability conditions
Verification & sources · governance
FAQ

Frequently asked questions

What are the limits and cautions when using Fluid Responsiveness Assessment?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Fluid Responsiveness Assessment upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Fluid Responsiveness Assessment calculated in practice? Can you show a worked example?
Inputs: Assessment method Fluid challenge (250–500 mL, measure SV change), Value (PLR/challenge = SV or CO increase %; PPV/SVV = variation %) 12 %, PPV/SVV applicability (mechanical ventilation Vt, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension) Met (or not a PPV/SVV method) → Result: Fluid responsiveness Responsive(Determination: Fluid challenge (250–500 mL) produced a stroke-volume increase of 12% (threshold ≥ 10%) → fluid-responsive (a fluid bolus may increase cardiac output), Management direction: With evidence of hypoperfusion (high lactate/oliguria/prolonged CRT), give fluids cautiously and reassess; stop volume expansion once non-responsive or perfusion improves, Note: Dynamic indices outperform static (CVP/single pressure predicts poorly). PLR and fluid challenge directly measure SV/CO change and remain applicable with spontaneous breathing and arrhythmia; PPV/SVV requires mechanical ventilation, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension. Give fluids on this basis only with signs of hypoperfusion) Inputs: Assessment method PPV / SVV (pulse-pressure / stroke-volume variation), Value (PLR/challenge = SV or CO increase %; PPV/SVV = variation %) 12 %, PPV/SVV applicability (mechanical ventilation Vt, sinus rhythm, no spontaneous breathing, no right-heart failure/intra-abdominal hypertension) Not met → Result: PPV/SVV Unreliable(Determination: PPV/SVV is reliable only with mechanical ventilation, sinus rhythm, no spontaneous breathing trigger, and no severe right-heart failure/intra-abdominal hypertension; the current conditions are not met, Recommendation: Switch to passive leg raise (PLR) or fluid challenge (directly measuring stroke-volume/cardiac-output change), which remain applicable with spontaneous breathing/arrhythmia, Basis: Dynamic indices outperform static (CVP predicts poorly); PPV/SVV applicability conditions)
Related tools