🧠 Cerebral Perfusion Pressure (CPP) & ICP Targets
UseUse to compute CPP from blood pressure and ICP and to check it against Brain Trauma Foundation targets.
SourceCarney N, et al. Brain Trauma Foundation severe-TBI guidelines, 4th ed. Neurosurgery 2017.
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
CPP upper limit [Pending update] — CPP is an optimization target, not 'higher is better' (original synthesis · not guideline verbatim).
When to use
Use to compute CPP from blood pressure and ICP and to check it against Brain Trauma Foundation targets.
How it works
MAP = DBP + (SBP − DBP)/3; CPP = MAP − ICP; severe-TBI target CPP [pending update]mmHg; ICP [pending update] mmHg triggers ICP-lowering therapy.
Key points
- CPP upper limit [Pending update] — CPP is an optimization target, not 'higher is better' (original synthesis · not guideline verbatim).
- Zero the arterial transducer at the tragus (≈ foramen of Monro) so MAP/CPP reflect cerebral, not cardiac, level.
- When autoregulation is impaired, cerebral blood flow follows CPP passively, making both hypo- and hypertension hazardous.
References
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Systolic BP SBP | 130 mmHg |
|---|---|
| Diastolic BP DBP | 70 mmHg |
| Intracranial pressure ICP | 18 mmHg |
→CPP72 mmHg
- Calculation：MAP = 90 mmHg (DBP + (SBP − DBP)/3); CPP = MAP − ICP = 90 − 18 = 72 mmHg
- CPP evaluation：Normal-high (above target; if maintained by vasopressors, watch for ARDS)
- ICP evaluation：ICP 18 (≤ 20 broadly acceptable)
Verification & sources · governance
FAQ
Frequently asked questions
- What are the limits and cautions when using Cerebral Perfusion Pressure (CPP) & ICP Targets?
- For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- Does Cerebral Perfusion Pressure (CPP) & ICP Targets upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Cerebral Perfusion Pressure (CPP) & ICP Targets calculated in practice? Can you show a worked example?
- Inputs: Systolic BP SBP 130 mmHg, Diastolic BP DBP 70 mmHg, Intracranial pressure ICP 18 mmHg → Result: CPP 72 mmHg（Calculation: MAP = 90 mmHg (DBP + (SBP − DBP)/3); CPP = MAP − ICP = 90 − 18 = 72 mmHg, CPP evaluation: Normal-high (above target; if maintained by vasopressors, watch for ARDS), ICP evaluation: ICP 18 (≤ 20 broadly acceptable)）