💉 Carboplatin Calvert Dose
Carboplatin Calvert: Dose=AUC×(GFR+25); optional CG and GFR cap 125.
Clinical takeaway
Calvert 1989; protocols override.
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When to use
Carboplatin dose estimate.
How it works
Dose = AUC × (GFR + 25)
Key points
- Calvert 1989; protocols override.
References
- Calvert AH et al. J Clin Oncol 1989
Decision support for licensed clinicians only; not a substitute for clinical judgement, diagnosis or local protocols.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Target AUC | 5 mg·min/mL |
|---|---|
| GFR / CrCl (or blank → CG) | 80 mL/min |
| Cap GFR at 125? | Yes |
| Age | 60 y |
| Weight | 70 kg |
| Sex | Male |
| Serum creatinine | 80 |
| Creatinine unit | µmol/L |
→Carboplatin dose525mg
- GFR used：80 mL/min
- GFR source：Direct entry
- AUC：5
Frequently asked questions
- What is Carboplatin Calvert Dose?
- Carboplatin Calvert: Dose=AUC×(GFR+25); optional CG and GFR cap 125.
- How is Carboplatin Calvert Dose calculated? What is the core formula?
- Dose = AUC × (GFR + 25) Compute from form inputs; protocols override.
- When is Carboplatin Calvert Dose used?
- Carboplatin dose estimate.
- How should Carboplatin Calvert Dose results be interpreted?
- Carboplatin Calvert: Dose=AUC×(GFR+25); optional CG and GFR cap 125.
- What are the key clinical points for Carboplatin Calvert Dose?
- Calvert 1989; protocols override.
- What are the limits and cautions when using Carboplatin Calvert Dose?
- For licensed clinicians. Protocols and labels override. Not a prescription. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
- How is Carboplatin Calvert Dose calculated in practice? Can you show a worked example?
- Inputs: Target AUC 5 mg·min/mL, GFR / CrCl (or blank → CG) 80 mL/min, Cap GFR at 125? Yes, Age 60 y, Weight 70 kg, Sex Male, Serum creatinine 80, Creatinine unit µmol/L → Result: Carboplatin dose 525 mg（GFR used: 80 mL/min, GFR source: Direct entry, AUC: 5）
💬 Peer discussion
Licensed clinicians only — about this Tool · Calvert carbo
Do not share identifiable patient information (PHI). Discuss principles and workflow only — not a substitute for clinical judgement.
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Starter prompts
AUC 目标切点：本院怎么选？
卡铂 Calvert 的目标 AUC（如 5 vs 6）在不同瘤种/方案里差异很大。你们科室如何定切点？有无因肾功能估算方法（CG vs CKD-EPI）导致剂量偏差的教训？请勿写可识别患者信息。
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