🧪 Age-Adjusted D-dimer Threshold (VTE)
UseWhen to use: after a validated unlikely/low–intermediate pre-test probability for PE or DVT, before imaging.
StrataBelow cut-off in an appropriate pathway lowers VTE likelihood; at/above cut-off does not confirm VTE — procee…
LimitsWhen not to use: high pre-test probability, pregnancy algorithms that… · Pitfall: using age-adjustment without Wells/Geneva (or equivalent) pr… · Do not use D-dimer alone to exclude VTE in high-probability patients.
SourceESC acute PE guideline (tool-page edition); China PTE 2018 on zh pages
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
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Methodology · worked example, guidelines & full notes
Age × 10 only if age > 50.
When to use
When to use: after a validated unlikely/low–intermediate pre-test probability for PE or DVT, before imaging.
How it works
Cut-off = 500 µg/L FEU if age ≤ 50; otherwise age (years) × 10 µg/L FEU.
Key points
- Age × 10 only if age > 50.
- FEU units (DDU ≈ half FEU — convert carefully).
- Next: Wells PE/DVT, PERC, then CTPA/duplex as indicated.
References
- [Guideline / primary source]ESC acute PE guideline (tool-page edition); China PTE 2018 on zh pages
- Douma RA, et al. BMJ 2010 (age-adjusted D-dimer)
- Righini M, et al. JAMA 2014 (ADJUST-PE)
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | 72 years |
|---|---|
| D-dimer result (optional) | 680 µg/L FEU |
→Age-adj. cut-offBelow cut-off
- Age-adjusted cut-off:720 µg/L FEU
- Rule:age (years) × 10 µg/L FEU
- Measured D-dimer:680 µg/L FEU
Verification & sources · governance
FAQ
Frequently asked questions
- Does Age-Adjusted D-dimer Threshold (VTE) upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is Age-Adjusted D-dimer Threshold (VTE) calculated in practice? Can you show a worked example?
- Inputs: Age 72 years, D-dimer result (optional) 680 µg/L FEU → Result: Age-adj. cut-off Below cut-off(Age-adjusted cut-off: 720 µg/L FEU, Rule: age (years) × 10 µg/L FEU, Measured D-dimer: 680 µg/L FEU)