🦴 2016 ACR/EULAR Primary Sjögren Classification
UseWhen to use: after entry dryness criterion and exclusion screen, when classification is needed.
StrataClassification aids research/structured care — not identical to clinical diagnosis alone.
LimitsWhen not to use: if published exclusions (HCV, IgG4, radiation, etc.)… · Pitfall: classifying without entry dryness/ESSDAI salivary item. · Seronegative disease still needs expert judgment.
SourceShiboski CH, et al. Arthritis Rheumatol / Ann Rheum Dis 2017 (2016 ACR/EULAR Sjögren)
This-shift next steps
After scoring: open the scene pack, peer scores, and the matching pathway. Local reference — no HIS write.
Paste the link in Slack, Teams, X, or LinkedIn — the preview image comes from this page’s Open Graph card.
Methodology · worked example, guidelines & full notes
Threshold ≥4.
When to use
When to use: after entry dryness criterion and exclusion screen, when classification is needed.
How it works
Focus-score≥1 biopsy (3) + anti-SSA (3) + OSS≥5 (1) + Schirmer≤5 (1) + UWS≤0.1 mL/min (1). Classify if ≥4.
Key points
- Threshold ≥4.
- Biopsy and SSA weigh 3 each.
- Next: ESSDAI activity / rheumatology.
References
- [Guideline / primary source]Shiboski CH, et al. Arthritis Rheumatol / Ann Rheum Dis 2017 (2016 ACR/EULAR Sjögren)
- CMA rheumatology Sjögren guidance on zh when cited
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 | No |
|---|---|
| Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) | No exclusions |
| Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 | No / not done (0) |
| Anti-SSA/Ro positive | No (0) |
| Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye | No (0) |
| Schirmer ≤5 mm/5 min in at least one eye | No (0) |
| Unstimulated whole saliva flow rate ≤0.1 mL/min | No (0) |
→ACR/EULAR SjögrenNot applicable
- Entry：Needs dryness entry (or ESSDAI salivary item)
| Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 | Yes (required) |
|---|---|
| Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) | Exclusion present — do not classify |
| Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 | Yes (3) |
| Anti-SSA/Ro positive | Yes (3) |
| Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye | Yes (1) |
| Schirmer ≤5 mm/5 min in at least one eye | Yes (1) |
| Unstimulated whole saliva flow rate ≤0.1 mL/min | Yes (1) |
→ACR/EULAR SjögrenExcluded
- Exclusion：Classification criteria not applied when exclusions present
Verification & sources · governance
FAQ
Frequently asked questions
- Does 2016 ACR/EULAR Primary Sjögren Classification upload patient data? Where is it calculated?
- Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
- How is 2016 ACR/EULAR Primary Sjögren Classification calculated in practice? Can you show a worked example?
- Inputs: Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 No, Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) No exclusions, Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 No / not done (0), Anti-SSA/Ro positive No (0), Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye No (0), Schirmer ≤5 mm/5 min in at least one eye No (0), Unstimulated whole saliva flow rate ≤0.1 mL/min No (0) → Result: ACR/EULAR Sjögren Not applicable（Entry: Needs dryness entry (or ESSDAI salivary item)） Inputs: Entry: ocular or oral dryness (≥1 of published questions) OR ESSDAI salivary-gland item ≥1 Yes (required), Exclusion criteria present (prior radiation, active HCV, AIDS, sarcoid, amyloid, GVHD, IgG4-related disease, etc.) Exclusion present — do not classify, Labial salivary gland: focal lymphocytic sialadenitis, focus score ≥1 Yes (3), Anti-SSA/Ro positive Yes (3), Ocular Staining Score ≥5 (or van Bijsterveld ≥4) in at least one eye Yes (1), Schirmer ≤5 mm/5 min in at least one eye Yes (1), Unstimulated whole saliva flow rate ≤0.1 mL/min Yes (1) → Result: ACR/EULAR Sjögren Excluded（Exclusion: Classification criteria not applied when exclusions present）