Guideline decision tool · Neurology
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Convulsive Status Epilepticus Staged Management — free guideline decision tool

Stage convulsive status epilepticus by time and give the first-line, second-line and refractory drug plan plus whole-course points. Instant, browser-side.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Current stage20–40 min (second-line)
IV accessYes

→Current actionSecond-line: IV antiseizure medication

  • Drug:IV antiseizure medication (choose one, full loading dose): sodium valproate, or levetiracetam, or (fos)phenytoin PE; the ESETT trial showed similar efficacy for all three (study finding)
  • Whole-course:Simultaneously address ABC (airway/breathing/circulation), cardiac/oximetry monitoring, check glucose (give 50% dextrose + thiamine if hypoglycemic), investigate and treat triggers (drug withdrawal, infection, electrolytes, toxins, etc.)
  • Timeline:A convulsion > 5 min is managed as SE; 5–20 min first-line, 20–40 min second-line, > 40 min or two lines failed is refractory; earlier control gives a better prognosis
Current stage5–20 min (first-line)
IV accessYes

→Current actionFirst-line: benzodiazepine

  • Drug:IV benzodiazepine: lorazepam (single dose), or diazepam IV push; may repeat once if not stopped in 5 minutes
  • Whole-course:Simultaneously address ABC (airway/breathing/circulation), cardiac/oximetry monitoring, check glucose (give 50% dextrose + thiamine if hypoglycemic), investigate and treat triggers (drug withdrawal, infection, electrolytes, toxins, etc.)
  • Timeline:A convulsion > 5 min is managed as SE; 5–20 min first-line, 20–40 min second-line, > 40 min or two lines failed is refractory; earlier control gives a better prognosis

Common questions

What is Convulsive Status Epilepticus Staged Management?

Stage convulsive status epilepticus by time and give the first-line, second-line and refractory drug plan plus whole-course points. Instant, browser-side.

How is Convulsive Status Epilepticus Staged Management calculated? What is the core formula?

5–20 min (first-line): full-dose benzodiazepine (lorazepam, or diazepam; IM midazolam if no IV). 20–40 min (second-line): IV valproate, levetiracetam, or (fos)phenytoin PE — similar efficacy in the ESETT trial (study finding). > 40 min / two lines failed (refractory): continuous anesthetic infusion + intubation + cEEG in ICU.

When is Convulsive Status Epilepticus Staged Management used?

Staged emergency management of convulsive status epilepticus.

What are the key clinical points for Convulsive Status Epilepticus Staged Management?

Treat as status epilepticus once a convulsion exceeds 5 minutes; earlier control gives a better prognosis. The ESETT trial showed similar efficacy for the three second-line agents (study finding) — choose by availability and patient factors. Throughout, address ABC, monitor cardiac/oxygenation, check glucose (give dextrose + thiamine if low) and find the trigger. Refractory status needs continuous IV anesthetic (midazolam/propofol/thiopental) with continuous EEG to target seizure control or burst-suppression.

What are the limits and cautions when using Convulsive Status Epilepticus Staged Management?

For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

Does Convulsive Status Epilepticus Staged Management upload patient data? Where is it calculated?

Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.

How is Convulsive Status Epilepticus Staged Management calculated in practice? Can you show a worked example?

Inputs: Current stage 20–40 min (second-line), IV access Yes → Result: Current action Second-line: IV antiseizure medication(Drug: IV antiseizure medication (choose one, full loading dose): sodium valproate, or levetiracetam, or (fos)phenytoin PE; the ESETT trial showed similar efficacy for all three (study finding), Whole-course: Simultaneously address ABC (airway/breathing/circulation), cardiac/oximetry monitoring, check glucose (give 50% dextrose + thiamine if hypoglycemic), investigate and treat triggers (drug withdrawal, infection, electrolytes, toxins, etc.), Timeline: A convulsion > 5 min is managed as SE; 5–20 min first-line, 20–40 min second-line, > 40 min or two lines failed is refractory; earlier control gives a better prognosis) Inputs: Current stage 5–20 min (first-line), IV access Yes → Result: Current action First-line: benzodiazepine(Drug: IV benzodiazepine: lorazepam (single dose), or diazepam IV push; may repeat once if not stopped in 5 minutes, Whole-course: Simultaneously address ABC (airway/breathing/circulation), cardiac/oximetry monitoring, check glucose (give 50% dextrose + thiamine if hypoglycemic), investigate and treat triggers (drug withdrawal, infection, electrolytes, toxins, etc.), Timeline: A convulsion > 5 min is managed as SE; 5–20 min first-line, 20–40 min second-line, > 40 min or two lines failed is refractory; earlier control gives a better prognosis)

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Stage convulsive status epilepticus by time and give the first-line, second-line and refractory drug plan plus whole-course points. Instant, browser-side.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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