Guideline decision tool · Hematology
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Simplified PESI (PE 30-day Mortality) — free guideline decision tool

Risk-stratify acute pulmonary embolism for 30-day mortality with the simplified PESI.

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Age > 80No
History of cancerNo
Chronic cardiopulmonary diseaseNo
Heart rate ≥ 110No
Systolic BP < 100No
SaO₂ < 90%No

→sPESI0

  • Interpretation:Low risk (~1% 30-day mortality) — consider outpatient treatment.
Age > 80Yes (+1)
History of cancerYes (+1)
Chronic cardiopulmonary diseaseYes (+1)
Heart rate ≥ 110Yes (+1)
Systolic BP < 100Yes (+1)
SaO₂ < 90%Yes (+1)

→sPESI6

  • Interpretation:High risk (~10%) — not suitable for outpatient management.

Common questions

What is Simplified PESI (PE 30-day Mortality)?

Risk-stratify acute pulmonary embolism for 30-day mortality with the simplified PESI.

How is Simplified PESI (PE 30-day Mortality) calculated? What is the core formula?

1 point each: age > 80, cancer, chronic cardiopulmonary disease, HR ≥ 110, SBP < 100, SaO₂ < 90%. 0 = low risk; ≥ 1 = high risk. Score 1 point each for age >80, cancer, chronic cardiopulmonary disease, HR ≥110, SBP <100 and SaO₂ <90%.

When is Simplified PESI (PE 30-day Mortality) used?

Identify low-risk PE potentially suitable for outpatient treatment.

How should Simplified PESI (PE 30-day Mortality) results be interpreted?

0 = low risk (~1% 30-day mortality) supporting outpatient pathways; ≥1 = not low risk.

What are the key clinical points for Simplified PESI (PE 30-day Mortality)?

A score of 0 (~1% mortality) supports outpatient management. Any positive item makes the patient high-risk. Combine with Hestia criteria and clinical judgement.

What are the limits and cautions when using Simplified PESI (PE 30-day Mortality)?

Any single positive item removes low-risk status — do not average items. Combine with Hestia/social factors before same-day discharge. Not a substitute for detecting high-risk PE with shock or marked RV failure. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

Does Simplified PESI (PE 30-day Mortality) upload patient data? Where is it calculated?

Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.

How is Simplified PESI (PE 30-day Mortality) calculated in practice? Can you show a worked example?

Inputs: Age > 80 No, History of cancer No, Chronic cardiopulmonary disease No, Heart rate ≥ 110 No, Systolic BP < 100 No, SaO₂ < 90% No → Result: sPESI 0(Interpretation: Low risk (~1% 30-day mortality) — consider outpatient treatment.) Inputs: Age > 80 Yes (+1), History of cancer Yes (+1), Chronic cardiopulmonary disease Yes (+1), Heart rate ≥ 110 Yes (+1), Systolic BP < 100 Yes (+1), SaO₂ < 90% Yes (+1) → Result: sPESI 6(Interpretation: High risk (~10%) — not suitable for outpatient management.)

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Run Simplified PESI (PE 30-day Mortality) now

Risk-stratify acute pulmonary embolism for 30-day mortality with the simplified PESI.

Open guideline tool →

For licensed clinicians. Not a substitute for clinical judgement.

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