SOFA Score (Sequential Organ Failure Assessment) — free guideline decision tool
Grade organ dysfunction in critical illness with the SOFA score across six systems.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Respiration (PaO₂/FiO₂) | < 300 (2) |
|---|---|
| Coagulation (platelets ×10³/µL) | < 100 (2) |
| Liver (bilirubin mg/dL) | 2.0–5.9 (2) |
| Cardiovascular | Dopamine ≤5 or dobutamine (2) |
| CNS (GCS) | 10–12 (2) |
| Renal (creatinine mg/dL) | 2.0–3.4 (2) |
→SOFA12/24
- ICU mortality (approx., initial SOFA, Ferreira 2001)：95.2% (>11)
- Sepsis-3：An acute rise of ≥ 2 points in suspected infection defines sepsis.
| Respiration (PaO₂/FiO₂) | ≥ 400 (0) |
|---|---|
| Coagulation (platelets ×10³/µL) | ≥ 150 (0) |
| Liver (bilirubin mg/dL) | < 1.2 (0) |
| Cardiovascular | MAP ≥ 70 (0) |
| CNS (GCS) | 15 (0) |
| Renal (creatinine mg/dL) | < 1.2 (0) |
→SOFA0/24
- ICU mortality (approx., initial SOFA, Ferreira 2001)：0%
- Sepsis-3：An acute rise of ≥ 2 points in suspected infection defines sepsis.
Common questions
What is SOFA Score (Sequential Organ Failure Assessment)?
Grade organ dysfunction in critical illness with the SOFA score across six systems.
How is SOFA Score (Sequential Organ Failure Assessment) calculated? What is the core formula?
0–4 points each for respiration, coagulation, liver, cardiovascular, CNS and renal (max 24). An acute rise of ≥ 2 in suspected infection = sepsis. Score six organ systems 0–4 (respiration PaO₂/FiO₂, coagulation platelets, liver bilirubin, cardiovascular MAP/vasopressors, CNS GCS, renal creatinine/urine).
When is SOFA Score (Sequential Organ Failure Assessment) used?
Track organ failure in the ICU and operationalise the Sepsis-3 sepsis definition.
How should SOFA Score (Sequential Organ Failure Assessment) results be interpreted?
Higher and rising totals mean worse organ dysfunction and mortality; infection plus acute ΔSOFA ≥ 2 supports Sepsis-3 sepsis (baseline often assumed 0).
What are the key clinical points for SOFA Score (Sequential Organ Failure Assessment)?
Higher and rising scores predict higher mortality. Sepsis-3: acute ΔSOFA ≥ 2 defines sepsis. Cardiovascular item uses vasopressor doses (µg/kg/min).
What are the limits and cautions when using SOFA Score (Sequential Organ Failure Assessment)?
Use trends, not a single snapshot. Cardiovascular points depend on accurate vasopressor dose recording. Lab timing and FiO₂ estimation affect respiratory and liver/renal items. SOFA-2 (JAMA 2025) has been published with revised thresholds and organ-support variables (NIV, ECMO, RRT, mechanical circulatory support); this page uses original SOFA as used by Sepsis-3. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does SOFA Score (Sequential Organ Failure Assessment) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is SOFA Score (Sequential Organ Failure Assessment) calculated in practice? Can you show a worked example?
Inputs: Respiration (PaO₂/FiO₂) < 300 (2), Coagulation (platelets ×10³/µL) < 100 (2), Liver (bilirubin mg/dL) 2.0–5.9 (2), Cardiovascular Dopamine ≤5 or dobutamine (2), CNS (GCS) 10–12 (2), Renal (creatinine mg/dL) 2.0–3.4 (2) → Result: SOFA 12 /24（ICU mortality (approx., initial SOFA, Ferreira 2001): 95.2% (>11), Sepsis-3: An acute rise of ≥ 2 points in suspected infection defines sepsis.） Inputs: Respiration (PaO₂/FiO₂) ≥ 400 (0), Coagulation (platelets ×10³/µL) ≥ 150 (0), Liver (bilirubin mg/dL) < 1.2 (0), Cardiovascular MAP ≥ 70 (0), CNS (GCS) 15 (0), Renal (creatinine mg/dL) < 1.2 (0) → Result: SOFA 0 /24（ICU mortality (approx., initial SOFA, Ferreira 2001): 0%, Sepsis-3: An acute rise of ≥ 2 points in suspected infection defines sepsis.）
Run SOFA Score (Sequential Organ Failure Assessment) now
Grade organ dysfunction in critical illness with the SOFA score across six systems.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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