SIRS Criteria Calculator — free guideline decision tool
Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Temperature > 38°C or < 36°C | No |
|---|---|
| Heart rate > 90/min | No |
| RR > 20/min or PaCO₂ < 32 mmHg | No |
| WBC > 12 or < 4 ×10⁹/L or > 10% bands | No |
→SIRS criteria0/4
- Interpretation:< 2 criteria.
| Temperature > 38°C or < 36°C | Yes |
|---|---|
| Heart rate > 90/min | Yes |
| RR > 20/min or PaCO₂ < 32 mmHg | Yes |
| WBC > 12 or < 4 ×10⁹/L or > 10% bands | Yes |
→SIRS criteria4/4
- Interpretation:≥ 2 criteria met = SIRS. With suspected infection, evaluate for sepsis.
Common questions
What is SIRS Criteria Calculator?
Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).
How is SIRS Criteria Calculator calculated? What is the core formula?
1 point each: temp > 38 or < 36°C; HR > 90; RR > 20 or PaCO₂ < 32; WBC > 12 or < 4 ×10⁹/L or > 10% bands. ≥ 2 = SIRS. Count SIRS criteria (temperature, HR, RR/PaCO₂, WBC/bands); ≥2 historically defined SIRS.
When is SIRS Criteria Calculator used?
Screen for systemic inflammation; with infection, prompt sepsis evaluation.
How should SIRS Criteria Calculator results be interpreted?
SIRS ≥2 is nonspecific; for suspected infection prefer qSOFA/SOFA (Sepsis-3) over SIRS alone.
What are the key clinical points for SIRS Criteria Calculator?
Non-specific — many non-infectious causes. Sepsis-3 favours qSOFA/SOFA for risk stratification. Still used for screening alongside clinical judgement.
What are the limits and cautions when using SIRS Criteria Calculator?
SIRS is neither sensitive nor specific for sepsis — avoid using it as the sole triage gate. Steroids, beta-blockers and hematologic disease alter HR/WBC criteria. Pair with lactate, cultures and organ-dysfunction assessment. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does SIRS Criteria Calculator upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is SIRS Criteria Calculator calculated in practice? Can you show a worked example?
Inputs: Temperature > 38°C or < 36°C No, Heart rate > 90/min No, RR > 20/min or PaCO₂ < 32 mmHg No, WBC > 12 or < 4 ×10⁹/L or > 10% bands No → Result: SIRS criteria 0 /4(Interpretation: < 2 criteria.) Inputs: Temperature > 38°C or < 36°C Yes, Heart rate > 90/min Yes, RR > 20/min or PaCO₂ < 32 mmHg Yes, WBC > 12 or < 4 ×10⁹/L or > 10% bands Yes → Result: SIRS criteria 4 /4(Interpretation: ≥ 2 criteria met = SIRS. With suspected infection, evaluate for sepsis.)
Run SIRS Criteria Calculator now
Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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