Guideline decision tool · Critical care
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SIRS Criteria Calculator — free guideline decision tool

Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).

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Computed locally — no data uploaded. For licensed clinicians.
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Guideline-based

Implements the decision logic from published clinical guidelines.

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Runs in your browser

No installation. Enter the patient's values and get a guideline recommendation instantly.

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Data stays local

Nothing is uploaded. Results are for licensed clinicians only.

Worked calculation

The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.

Temperature > 38°C or < 36°CNo
Heart rate > 90/minNo
RR > 20/min or PaCO₂ < 32 mmHgNo
WBC > 12 or < 4 ×10⁹/L or > 10% bandsNo

→SIRS criteria0/4

  • Interpretation:< 2 criteria.
Temperature > 38°C or < 36°CYes
Heart rate > 90/minYes
RR > 20/min or PaCO₂ < 32 mmHgYes
WBC > 12 or < 4 ×10⁹/L or > 10% bandsYes

→SIRS criteria4/4

  • Interpretation:≥ 2 criteria met = SIRS. With suspected infection, evaluate for sepsis.

Common questions

What is SIRS Criteria Calculator?

Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).

How is SIRS Criteria Calculator calculated? What is the core formula?

1 point each: temp > 38 or < 36°C; HR > 90; RR > 20 or PaCO₂ < 32; WBC > 12 or < 4 ×10⁹/L or > 10% bands. ≥ 2 = SIRS. Count SIRS criteria (temperature, HR, RR/PaCO₂, WBC/bands); ≥2 historically defined SIRS.

When is SIRS Criteria Calculator used?

Screen for systemic inflammation; with infection, prompt sepsis evaluation.

How should SIRS Criteria Calculator results be interpreted?

SIRS ≥2 is nonspecific; for suspected infection prefer qSOFA/SOFA (Sepsis-3) over SIRS alone.

What are the key clinical points for SIRS Criteria Calculator?

Non-specific — many non-infectious causes. Sepsis-3 favours qSOFA/SOFA for risk stratification. Still used for screening alongside clinical judgement.

What are the limits and cautions when using SIRS Criteria Calculator?

SIRS is neither sensitive nor specific for sepsis — avoid using it as the sole triage gate. Steroids, beta-blockers and hematologic disease alter HR/WBC criteria. Pair with lactate, cultures and organ-dysfunction assessment. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

Does SIRS Criteria Calculator upload patient data? Where is it calculated?

Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.

How is SIRS Criteria Calculator calculated in practice? Can you show a worked example?

Inputs: Temperature > 38°C or < 36°C No, Heart rate > 90/min No, RR > 20/min or PaCO₂ < 32 mmHg No, WBC > 12 or < 4 ×10⁹/L or > 10% bands No → Result: SIRS criteria 0 /4(Interpretation: < 2 criteria.) Inputs: Temperature > 38°C or < 36°C Yes, Heart rate > 90/min Yes, RR > 20/min or PaCO₂ < 32 mmHg Yes, WBC > 12 or < 4 ×10⁹/L or > 10% bands Yes → Result: SIRS criteria 4 /4(Interpretation: ≥ 2 criteria met = SIRS. With suspected infection, evaluate for sepsis.)

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Run SIRS Criteria Calculator now

Check the SIRS criteria for systemic inflammatory response (≥ 2 of 4).

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For licensed clinicians. Not a substitute for clinical judgement.

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For use by licensed clinicians and clinical researchers. Computed locally in your browser — no data is uploaded. Not a substitute for clinical judgement.

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