Sepsis Bundle (Hour-1) — free guideline decision tool
Turn lactate and shock status into the Surviving Sepsis Campaign Hour-1 bundle: fixed items, fluid target and vasopressor goal. Instant, browser-side.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Blood lactate | 3.2 mmol/L |
|---|---|
| Hypotension/shock (MAP < 65 or needs vasopressor) | Yes |
→ActionSeptic shock/hypoperfusion: start Hour-1 bundle
- Three fixed items：① Measure lactate immediately; ② obtain blood cultures (timing [Pending update]); ③ early empiric broad-spectrum antibiotics (within 1 hour for septic shock/high suspicion; aim within 3 hours for possible sepsis without shock)
- Fluid resuscitation：Fluids: at least 30 mL/kg crystalloid in the first 3 hours (population, fluid type and weight basis [Pending update])
- Vasopressor target：Persistent hypotension during/after fluids: norepinephrine first-line, maintain MAP ≥ 65 mmHg
| Blood lactate | 3.2 mmol/L |
|---|---|
| Hypotension/shock (MAP < 65 or needs vasopressor) | No |
→ActionSepsis: start Hour-1 bundle
- Three fixed items：① Measure lactate immediately; ② obtain blood cultures (timing [Pending update]); ③ early empiric broad-spectrum antibiotics (within 1 hour for septic shock/high suspicion; aim within 3 hours for possible sepsis without shock)
- Fluid resuscitation：Fluids: at least 30 mL/kg crystalloid in the first 3 hours (population, fluid type and weight basis [Pending update])
- Vasopressor target：No vasopressor needed yet (start if hypotension develops)
Common questions
What is Sepsis Bundle (Hour-1)?
Turn lactate and shock status into the Surviving Sepsis Campaign Hour-1 bundle: fixed items, fluid target and vasopressor goal. Instant, browser-side.
How is Sepsis Bundle (Hour-1) calculated? What is the core formula?
Three fixed items always apply (measure lactate, blood cultures, early broad-spectrum antibiotics). ≥ 30 mL/kg crystalloid in the first 3 h (population [Pending update]); persistent hypotension → norepinephrine to MAP ≥ 65. Source: SSC 2026 (recommendations 10, 13, 16–18, 53).
When is Sepsis Bundle (Hour-1) used?
Prompt the time-critical Hour-1 bundle for sepsis and septic shock at the bedside.
What are the key clinical points for Sepsis Bundle (Hour-1)?
Antibiotics within 1 h for septic shock or high suspicion; aim within 3 h for possible sepsis without shock. Norepinephrine is first-line; peripheral initiation [Pending update]. Fluid type and weight basis [Pending update]; reassess volume responsiveness dynamically rather than repeating fixed boluses. Lactate recheck [Pending update]; control the source and de-escalate by susceptibility.
What are the limits and cautions when using Sepsis Bundle (Hour-1)?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Sepsis Bundle (Hour-1) upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Sepsis Bundle (Hour-1) calculated in practice? Can you show a worked example?
Inputs: Blood lactate 3.2 mmol/L, Hypotension/shock (MAP < 65 or needs vasopressor) Yes → Result: Action Septic shock/hypoperfusion: start Hour-1 bundle（Three fixed items: ① Measure lactate immediately; ② obtain blood cultures (timing [Pending update]); ③ early empiric broad-spectrum antibiotics (within 1 hour for septic shock/high suspicion; aim within 3 hours for possible sepsis without shock), Fluid resuscitation: Fluids: at least 30 mL/kg crystalloid in the first 3 hours (population, fluid type and weight basis [Pending update]), Vasopressor target: Persistent hypotension during/after fluids: norepinephrine first-line, maintain MAP ≥ 65 mmHg） Inputs: Blood lactate 3.2 mmol/L, Hypotension/shock (MAP < 65 or needs vasopressor) No → Result: Action Sepsis: start Hour-1 bundle（Three fixed items: ① Measure lactate immediately; ② obtain blood cultures (timing [Pending update]); ③ early empiric broad-spectrum antibiotics (within 1 hour for septic shock/high suspicion; aim within 3 hours for possible sepsis without shock), Fluid resuscitation: Fluids: at least 30 mL/kg crystalloid in the first 3 hours (population, fluid type and weight basis [Pending update]), Vasopressor target: No vasopressor needed yet (start if hypotension develops)）
Run Sepsis Bundle (Hour-1) now
Turn lactate and shock status into the Surviving Sepsis Campaign Hour-1 bundle: fixed items, fluid target and vasopressor goal. Instant, browser-side.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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