Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway — free guideline decision tool
Brock (PanCan) and Mayo malignancy probabilities side by side, Herder after PET, and the BTS 2015 next step. Instant, browser-side.
Open guideline tool →Guideline-based
Implements the decision logic from published clinical guidelines.
Runs in your browser
No installation. Enter the patient's values and get a guideline recommendation instantly.
Data stays local
Nothing is uploaded. Results are for licensed clinicians only.
Worked calculation
The values below come from this tool's own example placeholders and are computed server-side with the formula shown on this page, so the arithmetic can be checked quickly. It demonstrates how to substitute values only — it is not clinical advice and not a real case.
| Age | 62 years |
|---|---|
| Sex | Male |
| Nodule maximum diameter (CT lung window) | 12 mm |
| Nodule type | Part-solid |
| Upper lobe | No |
| Spiculation | No |
| Total nodules on CT | 1 nodules |
| Emphysema | No |
| Family history of lung cancer | No |
| Ever smoker (current or former; Mayo) | Never |
| Extrathoracic cancer ≥5 years ago (Mayo) | No |
| PET-CT FDG uptake (Herder; leave blank if not done) | Faint (≤ mediastinal blood pool) |
→Herder9.8%
- Brock (PanCan)：7.1% (full model with spiculation)
- Mayo Clinic：5.3%
- Herder：9.8%
| Age | 62 years |
|---|---|
| Sex | Male |
| Nodule maximum diameter (CT lung window) | 12 mm |
| Nodule type | Solid |
| Upper lobe | No |
| Spiculation | No |
| Total nodules on CT | 1 nodules |
| Emphysema | No |
| Family history of lung cancer | No |
| Ever smoker (current or former; Mayo) | Never |
| Extrathoracic cancer ≥5 years ago (Mayo) | No |
| PET-CT FDG uptake (Herder; leave blank if not done) | Absent (≤ background) |
→Herder1.1%
- Brock (PanCan)：5.0% (full model with spiculation)
- Mayo Clinic：5.3%
- Herder：1.1%
Common questions
What is Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway?
Brock (PanCan) and Mayo malignancy probabilities side by side, Herder after PET, and the BTS 2015 next step. Instant, browser-side.
How is Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway calculated? What is the core formula?
Brock logit = −6.7892 + 0.0287(age−62) + 0.6011 female + 0.2961 family history + 0.2953 emphysema − 5.3854[(size/10)^−0.5 − 1.5811] + type (GGN −0.1276, part-solid 0.377) + 0.6581 upper lobe − 0.0824(count−4) + 0.7729 spiculation. Mayo logit = −6.8272 + 0.0391 age + 0.7917 smoker + 1.3388 cancer history + 0.1274 diameter + 1.0407 spiculation + 0.7838 upper lobe. Herder logit = −4.739 + 3.691 × Mayo + PET (faint 2.322 / moderate 4.617 / intense 4.771).
When is Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway used?
Solitary or multiple CT-detected lung nodules when deciding between CT surveillance, PET-CT and biopsy/excision.
What are the key clinical points for Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway?
Brock and Mayo shown together. Herder refines risk after PET. BTS thresholds: 10% and 70%. No follow-up below 5 mm.
What are the limits and cautions when using Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway?
For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.
Does Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway upload patient data? Where is it calculated?
Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.
How is Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway calculated in practice? Can you show a worked example?
Inputs: Age 62 years, Sex Male, Nodule maximum diameter (CT lung window) 12 mm, Nodule type Part-solid, Upper lobe No, Spiculation No, Total nodules on CT 1 nodules, Emphysema No… → Result: Herder 9.8%（Brock (PanCan): 7.1% (full model with spiculation), Mayo Clinic: 5.3%, Herder: 9.8%） Inputs: Age 62 years, Sex Male, Nodule maximum diameter (CT lung window) 12 mm, Nodule type Solid, Upper lobe No, Spiculation No, Total nodules on CT 1 nodules, Emphysema No… → Result: Herder 1.1%（Brock (PanCan): 5.0% (full model with spiculation), Mayo Clinic: 5.3%, Herder: 1.1%）
Run Lung Nodule Malignancy Risk (Brock / Mayo / Herder) + BTS Pathway now
Brock (PanCan) and Mayo malignancy probabilities side by side, Herder after PET, and the BTS 2015 next step. Instant, browser-side.
Open guideline tool →For licensed clinicians. Not a substitute for clinical judgement.
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