ACS GRACE Risk (framework) — free guideline decision tool

The GRACE risk score estimates in-hospital and 6-month mortality after an acute coronary syndrome from eight variables via a nonlinear, banded-lookup nomogram. This page frames the inputs and risk bands and links to the official calculator.

Eight variables — age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac markers — mapped through a nomogram. In-hospital bands: low ≤108, intermediate 109–140, high [pending update]. Collect the eight GRACE inputs (age, HR, SBP, creatinine, Killip, arrest, ST deviation, markers) and obtain the score from the official nomogram/calculator.

Use for NSTE-ACS risk stratification: invasive-strategy timing [pending update], interpreted alongside guidelines and the clinical picture.

In-hospital risk bands [pending update]. [Pending update] Some thresholds, grades and management recommendations on this page that conflict with current guidelines or are unverified are temporarily hidden pending verification against the guideline text.

The numerous band cut-points make the score unsuitable for on-platform reproduction; this page provides the inputs and risk bands and defers the exact score to the official calculator. (original synthesis · not guideline verbatim) In-hospital mortality bands: ≤108 (<1%), 109–140 (1–3%), [pending update](>3%); 6-month: ≤88, 89–118, >118. GRACE is a guideline-endorsed tool for timing the invasive strategy in NSTE-ACS.

Nonlinear nomogram — do not approximate with a linear sum on this page. Cardiac arrest and Killip class dominate risk; verify vitals and creatinine units. Use with troponin trajectory and bleeding risk when choosing anticoagulation/invasive strategy. For licensed clinicians and clinical researchers. Interpret results with history, investigations and local protocols; not a diagnosis or prescription, and not a substitute for multidisciplinary decision-making or local guidelines.

Calculation runs locally in the browser; inputs and results are not uploaded. For licensed clinicians only; interpret with history, investigations and local protocols — not a diagnosis or prescription.

Inputs: Show required inputs, risk bands and official link Show → Result: GRACE Reference framework (use official calculator)（Nature: The GRACE score converts 8 variables into a mortality probability via a banded look-up / nonlinear regression (nomogram) with numerous band cut-points. To avoid fabricating the look-up, this tool lists the required 8 items and risk bands and provides the official calculator; it does not output fabricated scores/probabilities, 8 inputs: Age, heart rate, systolic BP, serum creatinine, Killip class, cardiac arrest at admission, ECG ST-segment deviation, elevated cardiac necrosis markers, In-hospital mortality bands: Low ≤ 108 (< 1%), intermediate 109–140 (1–3%), high [pending update](> 3%)）